|Application ||WB, E|
|Calculated MW||82342 Da|
|Other Names||Synaptic vesicle glycoprotein 2C, SV2C, KIAA1054|
|Target/Specificity||This SV2C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 547-580 amino acids from the C-terminal region of human SV2C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SV2C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Note=Enriched in small synaptic vesicles and adrenal microsomes, not present in chromaffin granules Associated with both insulin granules and synaptic-like microvesicles in insulin-secreting cells of the pancreas (By similarity).|
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Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles (By similarity).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
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