|Application ||WB, E|
|Other Accession||P12391, Q8BMN3|
|Calculated MW||52729 Da|
|Other Names||Neuronal acetylcholine receptor subunit beta-3, CHRNB3|
|Target/Specificity||This CHRNB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-200 amino acids from the Central region of human CHRNB3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Precautions||CHRNB3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Elliott K.J.,et al.J. Mol. Neurosci. 7:217-228(1996).
Groot Kormelink P.J.,et al.FEBS Lett. 400:309-314(1997).
Keddache M.,et al.Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
Willoughby J.J.,et al.Neurosci. Lett. 155:136-139(1993).
If you have any additional inquiries please email technical services at email@example.com.