|Application ||WB, E|
|Other Accession||Q9JI91, P20111, Q3ZC55|
|Calculated MW||103854 Da|
|Other Names||Alpha-actinin-2, Alpha-actinin skeletal muscle isoform 2, F-actin cross-linking protein, ACTN2|
|Target/Specificity||This ACTN2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 352-386 amino acids from the Central region of human ACTN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACTN2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.|
|Cellular Location||Cytoplasm, myofibril, sarcomere, Z line Note=Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle|
|Tissue Location||Expressed in both skeletal and cardiac muscle.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.
Beggs A.H.,et al.J. Biol. Chem. 267:9281-9288(1992).
Tiso N.,et al.Biochem. Biophys. Res. Commun. 265:256-259(1999).
Gregory S.G.,et al.Nature 441:315-321(2006).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Faulkner G.,et al.J. Cell Biol. 146:465-475(1999).
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