|Application ||WB, E|
|Calculated MW||11832 Da|
|Other Names||High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC|
|Target/Specificity||This HMGA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 15-49 amino acids from the N-terminal region of human HMGA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HMGA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes. Plays a role in postnatal myogenesis, is involved in satellite cell activation (By similarity).|
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Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.
Patel U.A.,et al.Biochem. Biophys. Res. Commun. 201:63-70(1994).
Schoenmakers E.F.P.M.,et al.Nat. Genet. 10:436-444(1995).
Chau K.-Y.,et al.Nucleic Acids Res. 23:4262-4266(1995).
Ashar H.R.,et al.Genomics 31:207-214(1996).
Hauke S.,et al.Biochim. Biophys. Acta 1729:24-31(2005).
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