|Application ||WB, E|
|Calculated MW||25851 Da|
|Other Names||Extracellular superoxide dismutase [Cu-Zn], EC-SOD, SOD3|
|Target/Specificity||This SOD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 186-219 amino acids from the C-terminal region of human SOD3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SOD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.|
|Cellular Location||Secreted, extracellular space. Note=99% of EC-SOD is anchored to heparan sulfate proteoglycans in the tissue interstitium, and 1% is located in the vasculature in equilibrium between the plasma and the endothelium|
|Tissue Location||Expressed in blood vessels, heart, lung, kidney and placenta. Major SOD isoenzyme in extracellular fluids such as plasma, lymph and synovial fluid|
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Provided below are standard protocols that you may find useful for product applications.
Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen.
Hjalmarsson K.,et al.Proc. Natl. Acad. Sci. U.S.A. 84:6340-6344(1987).
Folz R.J.,et al.Genomics 22:162-171(1994).
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Adachi T.,et al.Free Radic. Biol. Med. 13:205-210(1992).
Nozik-Grayck E.,et al.Int. J. Biochem. Cell Biol. 37:2466-2471(2005).
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