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SKOR2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • IF - SKOR2 Antibody (C-term) AP21005c
    AP21005c staining SKOR2 in mouse cerebellum at embryonic stage 12.5 sections by Immunohistochemistry (IHC-P - 4%paraformaldehyde-fixed, cryopreserved in 30% sucrose/1X PBS for 30 hours, and then cut at a cryotome). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0.5 hour at room temperature. Samples were incubated with primary antibody (1/2000) for 1 hours at 37°C.Immunofluorescence image showing purkinje cell neurons staining on mouse cerebellum tissue.The nuclear counter stain is DAPI (blue).
    detail
  • WB - SKOR2 Antibody (C-term) AP21005c
    Western blot analysis of lysates from human cerebellum, human testis, mouse cerebellum tissue lysate (from left to right), using SKOR2 Antibody (C-term)(Cat. #AP21005c). AP21005c was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IF, E
Primary Accession Q2VWA4
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 105809 Da
Additional Information
Gene ID 652991
Other Names SKI family transcriptional corepressor 2, Functional Smad-suppressing element on chromosome 18, Fussel-18, LBX1 corepressor 1-like protein, Ladybird homeobox corepressor 1-like protein, SKOR2, CORL2, FUSSEL18
Target/Specificity This SKOR2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 741-775 amino acids from the C-terminal region of human SKOR2.
Dilution IF~~1:2000
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSKOR2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SKOR2 (HGNC:32695)
Synonyms CORL2, FUSSEL18
Function Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system.
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in cerebellum, spinal cord and testis. Isoform 2 is present in cerebellum (at protein level)
Research Areas
Citations (0)
citation

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Background

Exhibits transcriptional repressor activity (By similarity). Acts as a TGF-beta antagonist in the nervous system.

References

Arndt S.,et al.Lab. Invest. 85:1330-1341(2005).
Nusbaum C.,et al.Nature 437:551-555(2005).

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$ 365.00
$ 140.00
Cat# AP21005c
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