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LIFR Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - LIFR Antibody (C-term) AP21029c
    Anti-LIFR Antibody (C-term) at 1:2000 dilution + U-2OS whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 124 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - LIFR Antibody (C-term) AP21029c
    Western blot analysis of lysate from K562 cell line, using LIFR Antibody (C-term)(Cat. #AP21029c). AP21029c was diluted at 1:1000. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P42702
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 123743 Da
Additional Information
Gene ID 3977
Other Names Leukemia inhibitory factor receptor, LIF receptor, LIF-R, CD118, LIFR
Target/Specificity This LIFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1021-1055 amino acids from the C-terminal region of human LIFR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLIFR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LIFR
Function Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein
Research Areas
Citations (0)

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Background

Signal-transducing molecule. May have a common pathway with IL6ST. The soluble form inhibits the biological activity of LIF by blocking its binding to receptors on target cells.

References

Gearing D.P.,et al.EMBO J. 10:2839-2848(1991).
Wang Z.,et al.Submitted (AUG-1996) to the EMBL/GenBank/DDBJ databases.
Voz M.L.,et al.Oncogene 16:1409-1416(1998).
Dephoure N.,et al.Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Skiniotis G.,et al.Mol. Cell 31:737-748(2008).

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$ 295.00
$ 99.00
Cat# AP21029c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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