|Application ||WB, E|
|Calculated MW||269873 Da|
|Other Names||ATP-binding cassette sub-family A member 2, ATP-binding cassette transporter 2, ATP-binding cassette 2, ABCA2, ABC2, KIAA1062|
|Target/Specificity||This ABCA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1339-1373 amino acids from the Central region of human ABCA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ABCA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.|
|Cellular Location||Endosome membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Note=Forms discrete, punctate intracellular vesicles|
|Tissue Location||Highly expressed in the brain, whereas lower levels of expression is observed in kidney and liver|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Probable transporter, its natural substrate has not been found yet. May have a role in macrophage lipid metabolism and neural development.
Kaminski W.E.,et al.Biochem. Biophys. Res. Commun. 281:249-258(2001).
Vulevic B.,et al.Cancer Res. 61:3339-3347(2001).
Humphray S.J.,et al.Nature 429:369-374(2004).
Kikuno R.,et al.DNA Res. 6:197-205(1999).
Nakajima D.,et al.DNA Res. 9:99-106(2002).
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