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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MTTP Antibody (C-term)   

MTTP Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • FC - MTTP Antibody (C-term) AP21081a
    Flow cytometric analysis of Hela cells using MTTP Antibody (C-term)(green, Cat#AP21081a) compared to an isotype control of rabbit IgG(blue). AP21081a was diluted at 1:25 dilution. An Alexa Fluor® 488 goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody.
  • WB - MTTP Antibody (C-term) AP21081a
    Western blot analysis of lysates from HepG2 cell line, human liver, human kidney tissue (from left to right), using MTTP Antibody (C-term)(Cat. #AP21081a). AP21081a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, FC, E
Primary Accession P55157
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 99351 Da
Additional Information
Gene ID 4547
Other Names Microsomal triglyceride transfer protein large subunit, MTTP, MTP
Target/Specificity This MTTP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 878-911 amino acids from the C-terminal region of human MTTP.
Dilution FC~~1:25
WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMTTP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MTTP
Synonyms MTP
Function Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces (PubMed:23475612, PubMed:8939939, PubMed:26224785, PubMed:25108285, PubMed:22236406). Required for the secretion of plasma lipoproteins that contain apolipoprotein B (PubMed:23475612, PubMed:8939939, PubMed:26224785).
Cellular Location Endoplasmic reticulum. Note=Colocalizes with P4HB/PDI in the endoplasmic reticulum (PubMed:23475612, PubMed:26224785)
Tissue Location Liver and small intestine. Also found in ovary, testis and kidney.
Research Areas
Citations (0)

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Background

Catalyzes the transport of triglyceride, cholesteryl ester, and phospholipid between phospholipid surfaces. Required for the secretion of plasma lipoproteins that contain apolipoprotein B.

References

Shoulders C.C.,et al.Hum. Mol. Genet. 2:2109-2116(1993).
Sharp D.,et al.Nature 365:65-69(1993).
Sharp D.,et al.Biochemistry 33:9057-9061(1994).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hagan D.L.,et al.J. Biol. Chem. 269:28737-28744(1994).

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$ 295.00
$ 99.00
Cat# AP21081a
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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