|Application ||WB, E|
|Calculated MW||76257 Da|
|Other Names||Amphiphysin, AMPH, AMPH1|
|Target/Specificity||This AMPH antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 580-614 amino acids from the C-terminal region of human AMPH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AMPH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.|
|Cellular Location||Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton|
|Tissue Location||Neurons, certain endocrine cell types and spermatocytes|
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May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
David C.,et al.FEBS Lett. 351:73-79(1994).
Yamamoto R.,et al.Hum. Mol. Genet. 4:265-268(1995).
Floyd S.R.,et al.Mol. Med. 4:29-39(1998).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
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