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DNASE1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - DNASE1 Antibody (Center) AP21123a
    Western blot analysis of lysates from HepG2 cell line, mouse kidney tissue lysate(from left to right), using DNASE1 Antibody (Center)(Cat. #AP21123a). AP21123a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P24855
Other Accession P00639
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 31434 Da
Additional Information
Gene ID 1773
Other Names Deoxyribonuclease-1, Deoxyribonuclease I, DNase I, Dornase alfa, DNASE1, DNL1, DRNI
Target/Specificity This DNASE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 87-121 amino acids from the Central region of human DNASE1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDNASE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DNL1, DRNI
Function Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity).
Cellular Location Secreted. Nucleus envelope. Note=Secretory protein, stored in zymogen granules and found in the nuclear envelope
Tissue Location Principally in tissues of the digestive system. Highest levels found in urine, but also relatively abundant in semen and saliva
Research Areas
Citations (0)

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Among other functions, seems to be involved in cell death by apoptosis. Binds specifically to G-actin and blocks actin polymerization (By similarity).


Shak S.,et al.Proc. Natl. Acad. Sci. U.S.A. 87:9188-9192(1990).
Yasuda T.,et al.Ann. Hum. Genet. 59:1-15(1995).
Oliveri M.,et al.Eur. J. Immunol. 31:743-751(2001).
Kominato Y.,et al.FEBS J. 273:3094-3105(2006).
Martin J.,et al.Nature 432:988-994(2004).

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$ 295.00
$ 99.00
Cat# AP21123a
(40 western blots)
Availability: In Stock
Bulk Size
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