|Application ||WB, E|
|Calculated MW||10365 Da|
|Other Names||C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, IP-9, Interferon-inducible T-cell alpha chemoattractant, I-TAC, Small-inducible cytokine B11, CXCL11, ITAC, SCYB11, SCYB9B|
|Target/Specificity||This CXCL11 antibody is generated from a rabbit immunized with a recombinant protein of human CXCL11.|
|Precautions||CXCL11 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||ITAC, SCYB11, SCYB9B|
|Function||Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.|
|Tissue Location||High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine Also found in epidermal basal layer keratinocytes in skin disorders|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Rani M.R.S.,et al.J. Biol. Chem. 271:22878-22884(1996).
Jacobs K.A.,et al.Gene 198:289-296(1997).
Cole K.E.,et al.J. Exp. Med. 187:2009-2021(1998).
Tensen C.P.,et al.J. Invest. Dermatol. 112:716-722(1999).
Laich A.M.,et al.J. Interferon Cytokine Res. 19:505-513(1999).
If you have any additional inquiries please email technical services at email@example.com.