|Application ||WB, E|
|Calculated MW||75144 Da|
|Other Names||Acetoacetyl-CoA synthetase, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS, ACSF1|
|Target/Specificity||This AACS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 539-573 amino acids from the C-terminal region of human AACS.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AACS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).|
|Cellular Location||Cytoplasm, cytosol.|
|Tissue Location||Highly expressed in kidney, heart and brain, but low in liver.|
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Provided below are standard protocols that you may find useful for product applications.
Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).
Ohgami M.,et al.Biochem. Pharmacol. 65:989-994(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gu T.,et al.Mol. Cell. Biol. 18:4556-4564(1998).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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