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AACS Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - AACS Antibody (C-term) AP21166a
    All lanes : Anti-AACS Antibody (C-term) at 1:2000 dilution Lane 1: human kidney lysates Lane 2: rat brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 75 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q86V21
Reactivity Human, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 75144 Da
Additional Information
Gene ID 65985
Other Names Acetoacetyl-CoA synthetase, Acyl-CoA synthetase family member 1, Protein sur-5 homolog, AACS, ACSF1
Target/Specificity This AACS antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 539-573 amino acids from the C-terminal region of human AACS.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAACS Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AACS
Synonyms ACSF1
Function Converts acetoacetate to acetoacetyl-CoA in the cytosol (By similarity). Ketone body-utilizing enzyme, responsible for the synthesis of cholesterol and fatty acids (By similarity).
Cellular Location Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JMI1}
Tissue Location Highly expressed in kidney, heart and brain, but low in liver.
Citations (0)
citation

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Background

Activates acetoacetate to acetoacetyl-CoA. May be involved in utilizing ketone body for the fatty acid-synthesis during adipose tissue development (By similarity).

References

Ohgami M.,et al.Biochem. Pharmacol. 65:989-994(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gu T.,et al.Mol. Cell. Biol. 18:4556-4564(1998).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).

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$ 182.50
$ 70.00
Cat# AP21166a
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