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Mouse Ptk7 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - Mouse Ptk7 Antibody (C-term) AP21199b
    All lanes : Anti-Ptk7 Antibody (C-term) at 1:2000 dilution Lane 1: C2C12 whole cell lysates Lane 2: HepG2 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 118 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - Mouse Ptk7 Antibody (C-term) AP21199b
    Anti-Ptk7 Antibody (C-term) at 1:500 dilution + NIH/3T3 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 118 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8BKG3
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 117532 Da
Additional Information
Gene ID 71461
Other Names Inactive tyrosine-protein kinase 7, Protein chuzhoi, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, Ptk7
Target/Specificity This mouse Ptk7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 722-757 amino acids from the C-terminal region of mouse Ptk7.
Dilution WB~~1:500
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMouse Ptk7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Ptk7
Function Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Cellular Location Membrane; Single-pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells
Tissue Location Expressed at high levels in lung and un- pregnant uterus among adult tissues, and in the tail, limbs, somites, gut and craniofacial regions among embryonic tissues
Research Areas
Citations (0)

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Background

Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.

References

Jung J.-W.,et al.Gene 328:75-84(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Daigo Y.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Lu X.,et al.Nature 430:93-98(2004).
Gundry R.L.,et al.Mol. Cell. Proteomics 8:2555-2569(2009).

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$ 295.00
$ 99.00
Cat# AP21199b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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