|Application ||WB, E|
|Calculated MW||117532 Da|
|Other Names||Inactive tyrosine-protein kinase 7, Protein chuzhoi, Protein-tyrosine kinase 7, Pseudo tyrosine kinase receptor 7, Tyrosine-protein kinase-like 7, Ptk7|
|Target/Specificity||This mouse Ptk7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 722-757 amino acids from the C-terminal region of mouse Ptk7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Ptk7 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.|
|Cellular Location||Membrane; Single-pass type I membrane protein. Cell junction. Note=Colocalizes with MMP14 at cell junctions. Also localizes at the leading edge of migrating cells|
|Tissue Location||Expressed at high levels in lung and un- pregnant uterus among adult tissues, and in the tail, limbs, somites, gut and craniofacial regions among embryonic tissues|
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Inactive tyrosine kinase involved in Wnt signaling pathway. Component of both the non-canonical (also known as the Wnt/planar cell polarity signaling) and the canonical Wnt signaling pathway. Functions in cell adhesion, cell migration, cell polarity, proliferation, actin cytoskeleton reorganization and apoptosis. Has a role in embryogenesis, epithelial tissue organization and angiogenesis.
Jung J.-W.,et al.Gene 328:75-84(2004).
Carninci P.,et al.Science 309:1559-1563(2005).
Daigo Y.,et al.Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases.
Lu X.,et al.Nature 430:93-98(2004).
Gundry R.L.,et al.Mol. Cell. Proteomics 8:2555-2569(2009).
If you have any additional inquiries please email technical services at firstname.lastname@example.org.