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HNRNPU Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
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  • WB - HNRNPU Antibody (C-term) AP21212b
    All lanes : Anti-HNRNPU Antibody (C-term) at 1:2000 dilution Lane 1: Jurkat whole cell lysates Lane 2: NIH/3T3 whole cell lysates Lane 3: A431 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 91 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q00839
Reactivity Human, Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 90584 Da
Additional Information
Gene ID 3192
Other Names Heterogeneous nuclear ribonucleoprotein U, hnRNP U, Scaffold attachment factor A, SAF-A, p120, pp120, HNRNPU, HNRPU, SAFA, U211
Target/Specificity This HNRNPU antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 766-800 amino acids from the C-terminal region of human HNRNPU.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHNRNPU Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HNRNPU
Synonyms HNRPU, SAFA, U21.1
Function Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity).
Cellular Location Nucleus. Cytoplasm. Cell surface. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes.
Research Areas
Citations (0)

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Background

Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single- stranded DNA and RNA. Plays a role in the circadian regulation of the core clock component ARNTL/BMAL1 transcription (By similarity).

References

Kiledjian M.,et al.EMBO J. 11:2655-2664(1992).
Fackelmayer F.O.,et al.Biochim. Biophys. Acta 1217:232-234(1994).
Fackelmayer F.O.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Jordan P.,et al.Biochemistry 33:14696-14706(1994).

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$ 295.00
$ 99.00
Cat# AP21212b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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