|Application ||WB, E|
|Calculated MW||43997 Da|
|Other Names||Alpha-2A adrenergic receptor, Alpha-2A adrenoreceptor, Alpha-2A adrenoceptor, Alpha-2AAR, adra2a|
|Target/Specificity||This DANRE adra2a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 223-256 amino acids from the Central region of DANRE adra2a.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(DANRE) adra2a Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > oxymetazoline = epinephrine > norepinephrine.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. The order of potency for this receptor is dexmedetomidine > oxymetazoline = epinephrine > norepinephrine.
Ruuskanen J.O.,et al.Mol. Biol. Evol. 21:14-28(2004).
Ruuskanen J.O.,et al.Br. J. Pharmacol. 144:165-177(2005).
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