|Application ||WB, E|
|Calculated MW||50727 Da|
|Other Names||Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor, NPY5R, NPYR5|
|Target/Specificity||This NPY5R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 305-341 amino acids from the Central region of human NPY5R.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NPY5R Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Brain; hypothalamus.|
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Provided below are standard protocols that you may find useful for product applications.
Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders.
Hu Y.,et al.J. Biol. Chem. 271:26315-26319(1996).
Gerald C.,et al.Nature 382:168-171(1996).
Herzog H.,et al.Genomics 41:315-319(1997).
Kopatz S.A.,et al.Submitted (JUN-2003) to the EMBL/GenBank/DDBJ databases.
Hillier L.W.,et al.Nature 434:724-731(2005).
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