|Application ||WB, E|
|Calculated MW||52864 Da|
|Other Names||NF-kappa-B inhibitor epsilon, NF-kappa-BIE, I-kappa-B-epsilon, IkB-E, IkB-epsilon, IkappaBepsilon, NFKBIE, IKBE|
|Target/Specificity||This NFKBIE antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 191-224 amino acids from the Central region of human NFKBIE.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NFKBIE Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.|
|Tissue Location||Highly expressed in spleen, testis and lung, followed by kidney, pancreas, heart, placenta and brain. Also expressed in granulocytes and macrophages|
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Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. Inhibits DNA-binding of NF-kappa-B p50-p65 and p50-c-Rel complexes.
Whiteside S.T.,et al.EMBO J. 16:1413-1426(1997).
Mungall A.J.,et al.Nature 425:805-811(2003).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Li Z.,et al.Mol. Cell. Biol. 17:6184-6190(1997).
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