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(Mouse) Jag1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - (Mouse) Jag1 Antibody (C-term) AP21264b
    Anti-Jag1 Antibody (C-term)at 1:2000 dilution + mouse brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 134 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9QXX0
Reactivity Mouse
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 134164 Da
Additional Information
Gene ID 16449
Other Names Protein jagged-1, Jagged1, CD339, Jag1
Target/Specificity This Mouse Jag1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1191-1224 amino acids from the C-terminal region of Mouse Jag1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(Mouse) Jag1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name Jag1
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed in many tissues, with highest expression in brain, heart, muscle and thymus
Research Areas
Citations (0)

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Background

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). May regulate fibroblast growth factor-induced angiogenesis.

References

Shimizu K.,et al.J. Biol. Chem. 274:32961-32969(1999).
Loomes K.M.,et al.Hum. Mol. Genet. 8:2443-2449(1999).

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$ 295.00
$ 99.00
Cat# AP21264b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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