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INSM2 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96T92 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 59491 Da |
| Gene ID | 84684 |
|---|---|
| Other Names | Insulinoma-associated protein 2, Zinc finger protein IA-6, INSM2, IA6 |
| Target/Specificity | This INSM2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 192-227 amino acids from the Central region of human INSM2. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | INSM2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | INSM2 |
|---|---|
| Synonyms | IA6 |
| Function | May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons. |
| Cellular Location | Cytoplasm. Nucleus. |
| Tissue Location | Expressed in heart, liver, skeletal muscle, kidney and pancreas, and, to a lesser extent, in brain, lung and spleen. In the pancreas, expressed in islet cells, including insulin- and glucagon-producing alpha- and beta-cells, but not in acinar cells (at protein level). Detected in adrenal glands, particularly in the deeper layer of the cortex (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
May function as a growth suppressor or tumor suppressor in liver cells and in certain neurons.
References
Cai T.,et al.Submitted (APR-2000) to the EMBL/GenBank/DDBJ databases.
Halford S.,et al.Submitted (JUL-2012) to the EMBL/GenBank/DDBJ databases.
Ohira M.,et al.Cancer Lett. 197:63-68(2003).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Heilig R.,et al.Nature 421:601-607(2003).
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