|Application ||WB, E|
|Calculated MW||39706 Da|
|Other Names||Rhodopsin, rho, zfo2|
|Target/Specificity||This DANRE rho antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 62-93 amino acids from the human region of DANRE rho.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||(DANRE) rho Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4- didehydroretinal.|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Retinal rod photoreceptor cells, predominantly in the outer segments.|
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Provided below are standard protocols that you may find useful for product applications.
Visual pigments such as rhodopsin and porphyropsin are light-absorbing molecules that mediate vision. Rhodopsin consists of an apoprotein, opsin, covalently linked to 11-cis-retinal. This receptor is coupled to the activation of phospholipase C. Porphyropsin consists of opsin covalently linked to 11-cis 3,4- didehydroretinal.
Robinson J.,et al.Proc. Natl. Acad. Sci. U.S.A. 90:6009-6012(1993).
Robinson J.,et al.Vis. Neurosci. 12:895-906(1995).
Schmitt E.A.,et al.Vis. Neurosci. 16:601-605(1999).
Vihtelic T.S.,et al.Vis. Neurosci. 16:571-585(1999).
Kennedy B.N.,et al.J. Biol. Chem. 276:14037-14043(2001).
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