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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Zebrafish   >   (DANRE) aplnra Antibody (C-Term)   

(DANRE) aplnra Antibody (C-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - (DANRE) aplnra Antibody (C-Term) AP21299b
    All lanes : Anti-aplnra Antibody (C-Term) at 1:2000 dilution Lane 1: Zebrafish lysates Lane 2: Zebrafish muscle lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 41 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7SZP9
Reactivity Zebrafish
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 40649 Da
Additional Information
Gene ID 561935
Other Names Apelin receptor A, Angiotensin II receptor-like 1a, Angiotensin receptor-like 1a, G-protein coupled receptor APJ A, aplnra, agtrl1 {ECO:0000312|EMBL:ABI994701}, agtrl1a
Target/Specificity This DANRE aplnra antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 343-377 amino acids from the human region of DANRE aplnra.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions(DANRE) aplnra Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name aplnra
Synonyms agtrl1 {ECO:0000312|EMBL:ABI99470.1}, ag
Function Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1b in heart development.
Cellular Location Membrane; Multi-pass membrane protein
Tissue Location First expressed before epiboly in dorsal precursors. During epiboly, expressed in the enveloping layer, yolk syncytial layer and migrating mesendoderm. During segmentation stages, expressed in epithelial structures such as adaxial cells, border cells of the newly formed somites, developing lens, otic vesicles and venous vasculature
Research Areas
Citations (0)

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Background

Receptor for apelin coupled to G proteins that inhibit adenylate cyclase activity and plays a role in various processes in adults such as regulation of blood pressure, heart contractility, and heart failure. Also plays a key role in early development such as gastrulation and heart morphogenesis by acting as a receptor for apela hormone, promoting endoderm and mesendoderm cell migration and regulating the migration of cells fated to become myocardial progenitors, respectively (PubMed:24316148, PubMed:24407481). Acts redundantly with agtrl1b in heart development.

References

Tucker B.,et al.Gene Expr. Patterns 7:258-265(2007).
Scott I.C.,et al.Dev. Cell 12:403-413(2007).
Chng S.C.,et al.Dev. Cell 27:672-680(2013).
Pauli A.,et al.Science 343:1248636-1248636(2014).

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$ 295.00
$ 99.00
Cat# AP21299b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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