|Application ||WB, E|
|Calculated MW||47820 Da|
|Other Names||Type I inositol 1, 5-trisphosphate 5-phosphatase, 5PTase, INPP5A|
|Target/Specificity||This INPP5A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 306-340 amino acids from the C-terminal region of human INPP5A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||INPP5A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.|
|Cellular Location||Membrane; Lipid-anchor.|
|Tissue Location||Brain; high level in Purkinje cells.|
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Provided below are standard protocols that you may find useful for product applications.
Major isoenzyme hydrolyzing the calcium-mobilizing second messenger Ins(1,4,5)P3, this is a signal-terminating reaction.
de Smedt F.,et al.FEBS Lett. 347:69-72(1994).
Deloukas P.,et al.Nature 429:375-381(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Laxminarayan K.M.,et al.J. Biol. Chem. 269:17305-17310(1994).
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