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TACR1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TACR1 Antibody (C-term) AP21328b
    Anti-TACR1 Antibody (C-term)at 1:2000 dilution + THP-1 whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 46 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P25103
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 46251 Da
Additional Information
Gene ID 6869
Other Names Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1, TACR1, NK1R, TAC1R
Target/Specificity This TACR1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 363-397 amino acids from the C-terminal region of human TACR1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTACR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TACR1
Synonyms NK1R, TAC1R
Function This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.
Cellular Location Cell membrane; Multi-pass membrane protein.
Citations (0)

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Background

This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.

References

Takeda Y.,et al.Biochem. Biophys. Res. Commun. 179:1232-1240(1991).
Hopkins B.,et al.Biochem. Biophys. Res. Commun. 180:1110-1117(1991).
Gerard N.P.,et al.Biochemistry 30:10640-10646(1991).
Takahashi K.,et al.Eur. J. Biochem. 204:1025-1033(1992).
Fong T.M.,et al.Mol. Pharmacol. 41:24-30(1992).

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$ 295.00
$ 99.00
Cat# AP21328b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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