|Application ||IHC-P, WB, E|
|Calculated MW||46861 Da|
|Other Names||Neurexin-1-beta, Neurexin I-beta, NRXN1|
|Target/Specificity||This NRXN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 77-110 amino acids from the N-terminal region of human NRXN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NRXN1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Cell junction, synapse. Note=Localized on the pre- synaptic membrane.|
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Provided below are standard protocols that you may find useful for product applications.
Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).
Kleiderlein J.J.,et al.Hum. Genet. 103:666-673(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Chen X.,et al.Nat. Struct. Mol. Biol. 15:50-56(2008).
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