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NRXN1 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NRXN1 Antibody (N-term) AP21335a
    All lanes : Anti-NRXN1 Antibody (N-term) at 1:2000 dilution Lane 1: Human brain lysate Lane 2: Human cerebellum lysate Lane 3: U-87 MG whole cell lysate Lane 4: Mouse brain lysate Lane 5: Neuro-2a whole cell lysate Lane 6: Rat brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 50 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P58400
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 50424 Da
Antigen Region 77-110 aa
Additional Information
Gene ID 9378
Other Names Neurexin-1-beta, Neurexin I-beta, NRXN1
Target/Specificity This NRXN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 77-110 amino acids from the N-terminal region of human NRXN1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNRXN1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NRXN1 (HGNC:8008)
Function Neuronal cell surface protein involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. Plays a role in formation of synaptic junctions.
Cellular Location Presynaptic cell membrane {ECO:0000250|UniProtKB:Q63373}; Single-pass type I membrane protein {ECO:0000250|UniProtKB:Q63373}
Citations (0)
citation

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Background

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins. May play a role in formation or maintenance of synaptic junctions. May mediate intracellular signaling. May play a role in angiogenesis (By similarity).

References

Kleiderlein J.J.,et al.Hum. Genet. 103:666-673(1998).
Hillier L.W.,et al.Nature 434:724-731(2005).
Chen X.,et al.Nat. Struct. Mol. Biol. 15:50-56(2008).

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$ 365.00
$ 140.00
Cat# AP21335a
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