|Application ||WB, E|
|Calculated MW||39285 Da|
|Other Names||Endophilin-A3, EEN-B2, Endophilin-3, SH3 domain protein 2C, SH3 domain-containing GRB2-like protein 3, SH3GL3, CNSA3, SH3D2C|
|Target/Specificity||This SH3GL3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 250-282 amino acids from the C-terminal region of human SH3GL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SH3GL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).|
|Cellular Location||Cytoplasm. Early endosome membrane; Peripheral membrane protein Note=Associated with postsynaptic endosomes in hippocampal neurons. Associated with presynaptic endosomes in olfactory neurons (By similarity).|
|Tissue Location||Brain and testis.|
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Provided below are standard protocols that you may find useful for product applications.
Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Giachino C.,et al.Genomics 41:427-434(1997).
So C.W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Sittler A.,et al.Mol. Cell 2:427-436(1998).
Cestra G.,et al.J. Biol. Chem. 274:32001-32007(1999).
Trevaskis J.,et al.Endocrinology 146:3757-3764(2005).
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