(DANRE) mc4r Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | B0V1P1 |
Reactivity | Zebrafish |
Host | Rabbit |
Clonality | polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 36435 Da |
Antigen Region | 25-57 aa |
Gene ID | 286833 |
---|---|
Other Names | Melanocortin receptor 4, MC4-R, mc4r |
Target/Specificity | This DANRE mc4r antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the human region of DANRE mc4r. |
Dilution | WB~~1:2000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | (DANRE) mc4r Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | mc4r |
---|---|
Function | Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP). |
Cellular Location | Cell membrane; Multi-pass membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Receptor specific to the heptapeptide core common to adrenocorticotropic hormone and alpha-, beta-, and gamma-MSH. Plays a central role in energy homeostasis and somatic growth. This receptor is mediated by G proteins that stimulate adenylate cyclase (cAMP).
References
Ringholm A.,et al.J. Neurochem. 82:6-18(2002).
Logan D.W.,et al.Genomics 81:184-191(2003).
Howe K.,et al.Nature 496:498-503(2013).
Sebag J.A.,et al.Science 341:278-281(2013).
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