|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||39962 Da|
|Other Names||Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A|
|Target/Specificity||This SH3GL2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 245-279 amino acids from the C-terminal region of human SH3GL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SH3GL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Concentrated in presynaptic nerve terminals in neurons|
|Tissue Location||Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum|
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Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
Giachino C.,et al.Genomics 41:427-434(1997).
So C.W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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