|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||39962 Da|
|Other Names||Endophilin-A1, EEN-B1, Endophilin-1, SH3 domain protein 2A, SH3 domain-containing GRB2-like protein 2, SH3GL2, CNSA2, SH3D2A|
|Target/Specificity||This SH3GL2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 245-279 amino acids from the C-terminal region of human SH3GL2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SH3GL2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.|
|Cellular Location||Cytoplasm. Membrane; Peripheral membrane protein. Note=Concentrated in presynaptic nerve terminals in neurons|
|Tissue Location||Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum|
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Provided below are standard protocols that you may find useful for product applications.
Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
Giachino C.,et al.Genomics 41:427-434(1997).
So C.W.,et al.Submitted (MAR-1998) to the EMBL/GenBank/DDBJ databases.
Halleck A.,et al.Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
Kalnine N.,et al.Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
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