|Application ||IF, IHC-P, WB, E|
|Calculated MW||73262 Da|
|Other Names||Kinesin-like protein KIF22, Kinesin-like DNA-binding protein, Kinesin-like protein 4, KIF22, KID, KNSL4|
|Target/Specificity||This KIF22 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 423-456 amino acids from the Central region of human KIF22.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KIF22 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Kinesin family member that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA (By similarity). Plays a role in congression of laterally attached chromosomes in NDC80- depleted cells (PubMed:25743205).|
|Cellular Location||Nucleus. Cytoplasm, cytoskeleton|
|Tissue Location||Expressed in bone, cartilage, joint capsule, ligament, skin, and primary cultured chondrocytes|
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Provided below are standard protocols that you may find useful for product applications.
Kinesin family that is involved in spindle formation and the movements of chromosomes during mitosis and meiosis. Binds to microtubules and to DNA.
Tokai N.,et al.EMBO J. 15:457-467(1996).
Song J.,et al.Genomics 52:374-377(1998).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalnine N.,et al.Submitted (MAY-2003) to the EMBL/GenBank/DDBJ databases.
Totoki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
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