|Application ||WB, E|
|Calculated MW||37790 Da|
|Other Names||Ras association domain-containing protein 2, RASSF2, KIAA0168|
|Target/Specificity||This RASSF2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 123-156 amino acids from the Central region of human RASSF2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RASSF2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.|
|Cellular Location||Nucleus. Cytoplasm. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1|
|Tissue Location||Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.
Burbee D.G.,et al.Submitted (SEP-2002) to the EMBL/GenBank/DDBJ databases.
Nagase T.,et al.DNA Res. 3:17-24(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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