|Application ||WB, E|
|Calculated MW||44001 Da|
|Other Names||Forkhead box protein H1, Forkhead activin signal transducer 1, Fast-1, Forkhead activin signal transducer 2, Fast-2, Foxh1, Fast1, Fast2|
|Target/Specificity||This Mouse Foxh1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 290-322 amino acids from the C-terminal region of Mouse Foxh1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Mouse Foxh1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).|
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Provided below are standard protocols that you may find useful for product applications.
Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGT[GT][GT]ATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element).
Labbe E.,et al.Mol. Cell 2:109-120(1998).
Liu B.,et al.Mol. Cell. Biol. 19:424-430(1999).
Weisberg E.,et al.Mech. Dev. 79:17-27(1998).
Chen Y.,et al.Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases.
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