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JAG1 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - JAG1 Antibody (C-term) AP21532b
    Anti-JAG1 Antibody (C-term)at 1:2000 dilution + LNCaP whole cell lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 134 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P78504
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 133799 Da
Additional Information
Gene ID 182
Other Names Protein jagged-1, Jagged1, hJ1, CD339, JAG1, JAGL1
Target/Specificity This JAG1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1190-1224 amino acids from the C-terminal region of human JAG1.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsJAG1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JAG1
Synonyms JAGL1
Function Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed in adult and fetal tissues. In cervix epithelium expressed in undifferentiated subcolumnar reserve cells and squamous metaplasia. Expression is up-regulated in cervical squamous cell carcinoma. Expressed in bone marrow cell line HS-27a which supports the long-term maintenance of immature progenitor cells
Research Areas
Citations (0)

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Background

Ligand for multiple Notch receptors and involved in the mediation of Notch signaling. May be involved in cell-fate decisions during hematopoiesis. Seems to be involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation (By similarity). Enhances fibroblast growth factor-induced angiogenesis (in vitro).

References

Oda T.,et al.Genomics 43:376-379(1997).
Li L.,et al.Nat. Genet. 16:243-251(1997).
Li L.,et al.Immunity 8:43-55(1998).
Bash J.,et al.EMBO J. 18:2803-2811(1999).
Gray G.E.,et al.Am. J. Pathol. 154:785-794(1999).

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$ 99.00
Cat# AP21532b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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