|Application ||WB, E|
|Calculated MW||22949 Da|
|Other Names||Proteasome subunit beta type-3, Proteasome chain 13, Proteasome component C10-II, Proteasome theta chain, PSMB3|
|Target/Specificity||This PSMB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 150-185 amino acids from the Central region of human PSMB3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PSMB3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.|
|Cellular Location||Cytoplasm. Nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
Nothwang H.G.,et al.Biochim. Biophys. Acta 1219:361-368(1994).
Bienvenut W.V.,et al.Submitted (JUL-2008) to UniProtKB.
Lubec G.,et al.Submitted (MAR-2007) to UniProtKB.
Rasmussen H.H.,et al.Electrophoresis 13:960-969(1992).
Kristensen P.,et al.Biochem. Biophys. Res. Commun. 205:1785-1789(1994).
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