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DSTYK Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DSTYK Antibody (N-Term) AP21613a
    Anti-DSTYK Antibody (N-Term)at 1:2000 dilution + rat brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 105 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6XUX3
Reactivity Rat
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 105206 Da
Additional Information
Gene ID 25778
Other Names Dual serine/threonine and tyrosine protein kinase, Dusty protein kinase, Dusty PK, RIP-homologous kinase, Receptor-interacting serine/threonine-protein kinase 5, Sugen kinase 496, SgK496, DSTYK, KIAA0472, RIP5, RIPK5, SGK496
Target/Specificity This DSTYK antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 256-290 amino acids from human DSTYK.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDSTYK Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0472, RIP5, RIPK5, SGK496
Function Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.
Cellular Location Cytoplasm. Cell membrane {ECO:0000250|UniProtKB:Q6XUX1}. Apical cell membrane. Basolateral cell membrane. Cell junction {ECO:0000250|UniProtKB:Q6XUX1}. Note=Detected at apical cell-cell junctions. Colocalized with FGF receptors to the cell membrane (By similarity). Detected in basolateral and apical membranes of all tubular epithelia. {ECO:0000250|UniProtKB:Q6XUX1, ECO:0000269|PubMed:23862974}
Tissue Location Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines
Research Areas
Citations (0)

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Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death.


Peng J.,et al.Biochim. Biophys. Acta 1759:562-572(2006).
Zhao Z.,et al.Submitted (MAY-1998) to the EMBL/GenBank/DDBJ databases.
Gregory S.G.,et al.Nature 441:315-321(2006).
Seki N.,et al.DNA Res. 4:345-349(1997).
Zha J.,et al.Biochem. Biophys. Res. Commun. 319:298-303(2004).

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$ 295.00
$ 99.00
Cat# AP21613a
(40 western blots)
Availability: In Stock
Bulk Size
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