|Application ||WB, E|
|Calculated MW||11805 Da|
|Other Names||Signal peptidase complex subunit 1, 34--, Microsomal signal peptidase 12 kDa subunit, SPase 12 kDa subunit, SPCS1, SPC12|
|Target/Specificity||This SPCS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 66-100 amino acids from the Central region of human SPCS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPCS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.|
|Cellular Location||Microsome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum.
Zhang Q.-H.,et al.Genome Res. 10:1546-1560(2000).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Kalies K.-U.,et al.J. Biol. Chem. 271:3925-3929(1996).
Muzny D.M.,et al.Nature 440:1194-1198(2006).
Burkard T.R.,et al.BMC Syst. Biol. 5:17-17(2011).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.