|Application ||WB, E|
|Calculated MW||65750 Da|
|Other Names||Complement factor I, C3B/C4B inactivator, Complement factor I heavy chain, Complement factor I light chain, CFI, IF|
|Target/Specificity||This CFI (light chain) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 447-482 amino acids from the C-terminal region of human CFI (light chain).|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CFI (light chain) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.|
|Cellular Location||Secreted, extracellular space.|
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Provided below are standard protocols that you may find useful for product applications.
Responsible for cleaving the alpha-chains of C4b and C3b in the presence of the cofactors C4-binding protein and factor H respectively.
Catterall C.F.,et al.Biochem. J. 242:849-856(1987).
Goldberger G.,et al.J. Biol. Chem. 262:10065-10071(1987).
Hillier L.W.,et al.Nature 434:724-731(2005).
Minta J.O.,et al.Gene 208:17-24(1998).
Ullman C.G.,et al.FEBS Lett. 371:199-203(1995).
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