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NACA2 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - NACA2 Antibody (N-Term) AP21718a
    Anti-NACA2 Antibody (N-Term) at 1:2000 dilution + human skeletal muscle lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 23 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9H009
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 23223 Da
Additional Information
Gene ID 342538
Other Names Nascent polypeptide-associated complex subunit alpha-2, Alpha-NAC-like, Hom s 201, Nascent polypeptide-associated complex subunit alpha-like, NAC-alpha-like, NACA2, NACAL
Target/Specificity This NACA2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-69 amino acids from human NACA2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNACA2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NACA2
Synonyms NACAL
Function Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed specifically in testis and skeletal muscle.
Research Areas
Citations (0)

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Background

Prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. Also reduces the inherent affinity of ribosomes for protein translocation sites in the ER membrane (M sites) (By similarity).

References

Mossabeb R.,et al.J. Invest. Dermatol. 119:820-829(2002).
Marques A.C.,et al.PLoS Biol. 3:E357-E357(2005).
Mayya V.,et al.Sci. Signal. 2:RA46-RA46(2009).

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$ 295.00
$ 99.00
Cat# AP21718a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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