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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   TMPRSS11D Antibody (N-Term)   

TMPRSS11D Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TMPRSS11D Antibody (N-Term) AP21729a
    All lanes : Anti-TMPRSS11D Antibody (N-Term) at 1:2000 dilution Lane 1: human liver lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 46 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O60235
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 46263 Da
Additional Information
Gene ID 9407
Other Names Transmembrane protease serine 11D, 3421-, Airway trypsin-like protease, Transmembrane protease serine 11D non-catalytic chain, Transmembrane protease serine 11D catalytic chain, TMPRSS11D, HAT
Target/Specificity This TMPRSS11D antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 84-119 amino acids from human TMPRSS11D.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMPRSS11D Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMPRSS11D
Synonyms HAT
Function May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence.
Cellular Location Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted
Tissue Location Located in the cells of the submucosal serous glands of the bronchi and trachea
Research Areas
Citations (0)

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Background

May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence.

References

Yamaoka K.,et al.J. Biol. Chem. 273:11895-11901(1998).
Yasuoka S.,et al.Am. J. Respir. Cell Mol. Biol. 16:300-308(1997).
Bertram S.,et al.J. Virol. 87:6150-6160(2013).
Heurich A.,et al.J. Virol. 88:1293-1307(2014).

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$ 295.00
$ 99.00
Cat# AP21729a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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