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(DANRE) rab11fip4a Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q3LGD4 |
| Reactivity | Zebrafish |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 70946 Da |
| Antigen Region | 183-216 aa |
| Gene ID | 436806 |
|---|---|
| Other Names | Rab11 family-interacting protein 4A, FIP4-Rab11, Rab11-FIP4-A, zRab11-FIP4-A, rab11fip4a, rab11fip4 |
| Target/Specificity | This (DANRE) rab11fip4a antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-216 amino acids from the Central region of DANRE rab11fip4a. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | (DANRE) rab11fip4a Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | rab11fip4a |
|---|---|
| Synonyms | rab11fip4 |
| Function | Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). May play a role in differentiation during retinal development. |
| Cellular Location | Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis. |
| Tissue Location | Isoform 1 is predominantly expressed in neural tissues. Isoform B is expressed ubiquitously. In the developing retina, it is expressed in progenitors throughout the retina at early stages and becomes restricted to the ganglion cell layer and ciliary marginal zone as differentiation proceeds. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). May play a role in differentiation during retinal development.
References
Muto A.,et al.Dev. Biol. 292:90-102(2006).
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