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XPNPEP2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - XPNPEP2 Antibody (Center) AP21732c
    All lanes : Anti-XPNPEP2 Antibody (Center) at 1:2000 dilution Lane 1: A431 whole cell lysate Lane 2: HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 76 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O43895
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 75625 Da
Additional Information
Gene ID 7512
Other Names Xaa-Pro aminopeptidase 2, Aminoacylproline aminopeptidase, Membrane-bound aminopeptidase P, Membrane-bound APP, Membrane-bound AmP, mAmP, X-Pro aminopeptidase 2, XPNPEP2
Target/Specificity This XPNPEP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 373-407 amino acids from the Central region of human XPNPEP2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsXPNPEP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XPNPEP2
Function Membrane-bound metalloprotease which catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Arg-Pro-Pro. May play a role in the metabolism of the vasodilator bradykinin.
Cellular Location Cell membrane {ECO:0000250|UniProtKB:Q95333}; Lipid-anchor, GPI-anchor {ECO:0000250|UniProtKB:Q95333}
Tissue Location Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary
Research Areas
Citations (0)
citation

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Background

A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.

References

Venema R.C.,et al.Biochim. Biophys. Acta 1354:45-48(1997).
Sprinkle T.J.C.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ryan J.W.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Duan Q.L.,et al.Am. J. Hum. Genet. 77:617-626(2005).

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$ 182.50
$ 70.00
Cat# AP21732c
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