|Application ||WB, E|
|Calculated MW||75625 Da|
|Other Names||Xaa-Pro aminopeptidase 2, Aminoacylproline aminopeptidase, Membrane-bound aminopeptidase P, Membrane-bound APP, Membrane-bound AmP, mAmP, X-Pro aminopeptidase 2, XPNPEP2|
|Target/Specificity||This XPNPEP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 373-407 amino acids from the Central region of human XPNPEP2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||XPNPEP2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor.|
|Tissue Location||Expressed in kidney, lung, heart, placenta, liver, small intestine and colon. No expression in brain, skeletal muscle, pancreas, spleen, thymus, prostate, testis and ovary|
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Provided below are standard protocols that you may find useful for product applications.
A metalloprotease that may play a role in the inflammatory process and other reactions produced in response to injury or infection. May also play a role in the metabolism of the vasodilator bradykinin.
Venema R.C.,et al.Biochim. Biophys. Acta 1354:45-48(1997).
Sprinkle T.J.C.,et al.Submitted (SEP-2000) to the EMBL/GenBank/DDBJ databases.
Ryan J.W.,et al.Submitted (OCT-1999) to the EMBL/GenBank/DDBJ databases.
Ross M.T.,et al.Nature 434:325-337(2005).
Duan Q.L.,et al.Am. J. Hum. Genet. 77:617-626(2005).
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