|Application ||WB, E|
|Calculated MW||61252 Da|
|Other Names||Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1A, Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1, PDE1A|
|Target/Specificity||This PDE1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57 amino acids from human PDE1A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDE1A Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.|
|Tissue Location||Several tissues, including brain, kidney, testes and heart|
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Provided below are standard protocols that you may find useful for product applications.
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
Loughney K.,et al.J. Biol. Chem. 271:796-806(1996).
Michibata H.,et al.Biochim. Biophys. Acta 1517:278-287(2001).
Fidock M.D.,et al.Cell. Signal. 14:53-60(2002).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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