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PDE1A Antibody (N-Term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P54750 |
| Reactivity | Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 61252 Da |
| Gene ID | 5136 |
|---|---|
| Other Names | Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1A, Cam-PDE 1A, 61 kDa Cam-PDE, hCam-1, PDE1A |
| Target/Specificity | This PDE1A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 23-57 amino acids from human PDE1A. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PDE1A Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PDE1A (HGNC:8774) |
|---|---|
| Function | Calcium/calmodulin-dependent cyclic nucleotide phosphodiesterase with a dual specificity for the second messengers cGMP and cAMP, which are key regulators of many important physiological processes. Has a higher efficiency with cGMP compared to cAMP. |
| Tissue Location | Several tissues, including brain, kidney, testes and heart |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a higher affinity for cGMP than for cAMP.
References
Loughney K.,et al.J. Biol. Chem. 271:796-806(1996).
Michibata H.,et al.Biochim. Biophys. Acta 1517:278-287(2001).
Fidock M.D.,et al.Cell. Signal. 14:53-60(2002).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
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