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RAE1 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P78406 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 40968 Da |
| Gene ID | 8480 |
|---|---|
| Other Names | mRNA export factor, Rae1 protein homolog, mRNA-associated protein mrnp 41, RAE1, MRNP41 |
| Target/Specificity | This RAE1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 128-162 amino acids from the Central region of human RAE1. |
| Dilution | WB~~1:2000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RAE1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RAE1 |
|---|---|
| Synonyms | MRNP41 |
| Function | Acts as a mRNA export factor involved in nucleocytoplasmic transport (PubMed:33849972, PubMed:20498086). Plays a role in mitotic bipolar spindle formation (PubMed:17172455). May function in attaching cytoplasmic mRNPs to the cytoskeleton both directly or indirectly (PubMed:17172455). |
| Cellular Location | Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, spindle pole. Nucleus envelope. Note=Recruited from interphase nuclei to spindle MTs during mitosis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
Binds mRNA. May function in nucleocytoplasmic transport and in directly or indirectly attaching cytoplasmic mRNPs to the cytoskeleton.
References
Bharathi A.,et al.Gene 198:251-258(1997).
Kraemer D.M.,et al.Proc. Natl. Acad. Sci. U.S.A. 94:9119-9124(1997).
Lu L.,et al.Submitted (JUL-2003) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Deloukas P.,et al.Nature 414:865-871(2001).
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