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DMRT2 Antibody (N-Term)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - DMRT2 Antibody (N-Term) AP21761a
    Anti-DMRT2 Antibody (N-Term) at 1:2000 dilution + human kidney lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 62 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9Y5R5
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit IgG
Calculated MW 61814 Da
Additional Information
Gene ID 10655
Other Names Doublesex- and mab-3-related transcription factor 2, Doublesex-like 2 protein, DSXL-2, DMRT2, DSXL2
Target/Specificity This DMRT2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 222-256 amino acids from human DMRT2.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDMRT2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DMRT2
Synonyms DSXL2
Function Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00070}.
Tissue Location Expressed in testis, kidney and skeletal muscle.
Citations (0)
citation

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Background

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

References

Raymond C.S.,et al.Hum. Mol. Genet. 8:989-996(1999).
Ottolenghi C.,et al.Genomics 64:179-186(2000).
Calvari V.,et al.Genomics 65:203-212(2000).
Humphray S.J.,et al.Nature 429:369-374(2004).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.

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$ 182.50
$ 70.00
Cat# AP21761a
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