|Application ||WB, E|
|Calculated MW||70841 Da|
|Antigen Region||547-576 aa|
|Other Names||Ubiquilin-3, UBQLN3|
|Target/Specificity||This UBQLN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 547-576 amino acids from the C-terminal region of human UBQLN3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UBQLN3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Testis specific.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an ubiquitin-like protein (ubiquilin) that shares high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain a N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This gene is specifically expressed in the testis, and proposed to regulate cell-cycle progression during spermatogenesis.
Conklin, D., et al., Gene 249 (1-2), 91-98 (2000) (): ().
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