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MAZ Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MAZ Antibody (Center) AP21798c
    All lanes : Anti-MAZ Antibody (Center) at 1:1000 dilution Lane 1: A549 whole cell lysate Lane 2: CCRF-CEM whole cell lysate Lane 3: Hela whole cell lysate Lane 4: HT-1080 whole cell lysate Lane 5: THP-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 49 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P56270
Reactivity Human
Host Rabbit
Clonality polyclonal
Isotype Rabbit Ig
Calculated MW 48608 Da
Additional Information
Gene ID 4150
Other Names Myc-associated zinc finger protein, MAZI, Pur-1, Purine-binding transcription factor, Serum amyloid A-activating factor-1, SAF-1, Transcription factor Zif87, ZF87, Zinc finger protein 801, MAZ, ZNF801
Target/Specificity This MAZ antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 295-327 amino acids from the Central region of human MAZ.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMAZ Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAZ
Synonyms ZNF801
Function May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.
Cellular Location Nucleus. Note=In brains of Alzheimer disease patients, present in a plaque- like structures
Tissue Location Present in kidney, liver and brain. In the brain, highest levels are found in motor cortex and midfrontal cortex (at protein level).
Citations (0)

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Background

May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.

References

Bossone S.A.,et al.Proc. Natl. Acad. Sci. U.S.A. 89:7452-7456(1992).
Pyrc J.J.,et al.Biochemistry 31:4102-4110(1992).
Tsutsui H.,et al.Biochem. Biophys. Res. Commun. 226:801-809(1996).
Parks C.L.,et al.J. Biol. Chem. 271:4417-4430(1996).
Song J.,et al.J. Biol. Chem. 273:20603-20614(1998).

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$ 295.00
$ 99.00
Cat# AP21798c
Size:
Quantity:
(40 western blots)
Availability: In Stock
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