|Application ||WB, E|
|Reactivity||Human, Mouse, Rat|
|Calculated MW||80760 Da|
|Other Names||Calcium/calmodulin-dependent 3', 5'-cyclic nucleotide phosphodiesterase 1C, Cam-PDE 1C, hCam-3, PDE1C|
|Target/Specificity||This PDE1C antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 375-409 amino acids from the Central region of human PDE1C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDE1C Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.|
|Tissue Location||Expressed in several tissues, including brain and heart|
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Provided below are standard protocols that you may find useful for product applications.
Cyclic nucleotide phosphodiesterase with a dual- specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. Has a high affinity for both cAMP and cGMP.
Loughney K.,et al.J. Biol. Chem. 271:796-806(1996).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Hillier L.W.,et al.Nature 424:157-164(2003).
Oppermann F.S.,et al.Mol. Cell. Proteomics 8:1751-1764(2009).
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