|Application ||WB, E|
|Calculated MW||25919 Da|
|Other Names||Ribosyldihydronicotinamide dehydrogenase [quinone], NRH dehydrogenase [quinone] 2, NRH:quinone oxidoreductase 2, Quinone reductase 2, QR2, NQO2, NMOR2|
|Target/Specificity||This NQO2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 21-52 amino acids from human NQO2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NQO2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.|
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Provided below are standard protocols that you may find useful for product applications.
The enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinones involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
Jaiswal A.K.,et al.Biochemistry 29:1899-1906(1990).
Jaiswal A.K.,et al.J. Biol. Chem. 269:14502-14508(1994).
Iida A.,et al.Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mungall A.J.,et al.Nature 425:805-811(2003).
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