|Application ||WB, E|
|Calculated MW||229832 Da|
|Other Names||Ral GTPase-activating protein subunit alpha-1, GAP-related-interacting partner to E12, GRIPE, GTPase-activating Rap/Ran-GAP domain-like 1, Tuberin-like protein 1, p240, RALGAPA1, GARNL1, KIAA0884, TULIP1|
|Target/Specificity||This RALGAPA1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 735-768 amino acids from human RALGAPA1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RALGAPA1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GARNL1, KIAA0884, TULIP1|
|Function||Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.|
|Cellular Location||Cytoplasm. Nucleus. Note=Translocated to the nucleus, when associated with TCF3/E12.|
|Tissue Location||Widely expressed.|
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Provided below are standard protocols that you may find useful for product applications.
Catalytic subunit of the heterodimeric RalGAP1 complex which acts as a GTPase activator for the Ras-like small GTPases RALA and RALB.
Schwarzbraun T.,et al.Genomics 84:577-586(2004).
Shirakawa R.,et al.J. Biol. Chem. 284:21580-21588(2009).
Nagase T.,et al.DNA Res. 5:355-364(1998).
Heilig R.,et al.Nature 421:601-607(2003).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
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