|Application ||WB, E|
|Other Accession||Q08DE5, Q61070, Q4KM77|
|Calculated MW||38965 Da|
|Other Names||Etoposide-induced protein 24 homolog, p53-induced gene 8 protein, EI24, PIG8|
|Target/Specificity||This EI24 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human EI24.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EI24 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).|
|Cellular Location||Nucleus membrane; Multi-pass membrane protein. Cytoplasm. Endoplasmic reticulum membrane; Multi-pass membrane protein|
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Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy (By similarity).
Polyak K.,et al.Nature 389:300-306(1997).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Mural R.J.,et al.Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
Gentile M.,et al.Oncogene 20:7753-7760(2001).
Olsen J.V.,et al.Cell 127:635-648(2006).
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