|Application ||WB, E|
|Calculated MW||25943 Da|
|Other Names||Transmembrane emp24 domain-containing protein 4, Endoplasmic reticulum stress-response protein 25, ERS25, GMP25iso, Putative NF-kappa-B-activating protein 156, p24 family protein alpha-3, p24alpha3, TMED4, ERS25|
|Target/Specificity||This TMED4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 130-161 amino acids from the Central region of human TMED4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMED4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein|
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Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kim J.W.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
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