|Application ||WB, E|
|Calculated MW||25943 Da|
|Other Names||Transmembrane emp24 domain-containing protein 4, Endoplasmic reticulum stress-response protein 25, ERS25, GMP25iso, Putative NF-kappa-B-activating protein 156, p24 family protein alpha-3, p24alpha3, TMED4, ERS25|
|Target/Specificity||This TMED4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 130-161 amino acids from the Central region of human TMED4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMED4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
Involved in vesicular protein trafficking, mainly in the early secretory pathway. targeting. Involved in the maintenance of the Golgi apparatus. Appears to play a role in the biosynthesis of secreted cargo including processing. Involved in endoplasmic reticulum stress response. May play a role in the regulation of heat-shock response and apoptosis (By similarity).
Ota T.,et al.Nat. Genet. 36:40-45(2004).
Bechtel S.,et al.BMC Genomics 8:399-399(2007).
Scherer S.W.,et al.Science 300:767-772(2003).
Mural R.J.,et al.Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
Kim J.W.,et al.Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
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